quantum biology enzymes

These quantum effects range from tunnelling, as observed in enzyme processes and conjectured in olfaction, to the observations of quantum coherent superpositions in photosynthetic energy capture, and finally to entanglement—Einstein's 'spooky action at a distance'—in a possible mechanism for magneto-detection in animals. Found insideThis is followed by separate chapters on estimating the rate parameters of elementary reactions; the use of correlation diagrams to interpret organic reactions; perturbation of reaction rates by substituents; and inorganic reactions. Now the term "quantum" may seem over-used at times, and quantum biology on first glance, may seem like something made up just with buzzwords. That might mean explaining a topic from an anatomy class or exploring a topic from medical history.💻 C O N T A C T 💻If you’d like to sponsor a video or have other business inquiries: patkellyteaches [at] gmail.com#corporis #anatomy #medicalhistory It is a highly evolved symbolic system of chemical self-description. The word “quantum” refers to those wave-particle packets of energy. Quantum-Chemical Descriptors of Hydroxychloroquine and Remdesivir. QUANTUM BIOLOGY & PHOTOSYNTHESIS. He has written ten books, translated into over twenty languages. Thence the question why nature appears quantized is simply a consequence of the fact that information itself is quantized by necessity. The FMO complex appears in green sulfur bacteria that live in the Black Sea and other sulfide-rich waters. Quantum Biology studies the dynamical influence of quantum effects in biological systems. “We really have no idea about what the binding partners are of the cryptochromes in the context of magnetic sensing. Back in the 1970s, Schulten originally had suggested that, in the presence of light, unpaired spins coupled in a way that was sensitive to a magnetic field. Supplements that claim to supercharge your T-cells, make your antibodies hum and otherwise make you invincible are all bunk, and scientists should speak out more about this misinformation. true for enzyme reactions that involve a particular quantum mechanical phenomenon known as But in doing the kinetic isotopic effect experiments with enzymes such as alcohol dehydrogenase and soybean lipoxygenase for more than two decades, Klinman and colleagues showed that hydrogen tunneling was occurring in biological molecules at room temperature. A new theory explains how fragile quantum states may be able to exist for hours or even days in our warm, wet brain. (In their book, Al-Khalili and McFadden call that paper “one of the classic papers of quantum biology.”). The fact that electrons can tunnel, which means to cut across an energy barrier instead of going over it, is undisputed. Quantum biology and Ockham's razor. I used to work in the clinical setting as a certified athletic trainer, physical therapy aide, and a certified strength and conditioning specialist. “It was lasting, interestingly, on the timescale of the energy transfer times in these complexes.”. In this review, we summarise the latest progress in quantum biology, including the areas of enzyme-catalysed reactions, photosynthesis, spin-dependent reactions, DNA, fluorescent proteins, and ion channels. But notice that culture changers are (with or without knowing) presenting their own very original hypotheses, which when entertainingly tested support scientific theory that qualifies as ID (click my screenname for .pdf of the text). Quantum Biology Workshop, November, 2018. Found insideThis book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and ... That’s not enough for a compass.”. The investigators used an ultrafast spectroscopic technique that allowed them to study the complex. Would you snort with derision or give the idea some serious thought? Whereas conversely, if consciousness precedes material reality then consciousness will be found to have a special position within material reality. The data suggested that the energy was traveling by multiple routes in the chlorophyll molecules simultaneously, all within a couple of picoseconds. As you say, this is... –, Fascinating - the left caught between persecuting the Native Americans for their religious belief and accepting creationism. Physicists who pondered the atomic and molecular processes of life included Max Delbrück and Erwin Schrödinger. Or can the interactions be relatively accurately be understood using simply classical mechanics principles? In this provocative book, he argues that fashion, faith, and fantasy, while sometimes productive and even essential in physics, may be leading today's researchers astray in three of the field's most important areas—string theory, quantum ... Watch part 2 over on Pat's channel! What I’m explaining is the Science 101 level of detail, as shown in this “Everything Is Energy” video: Idiosyncratic. Stewart Wills. Only the universal validity of the superposition principle allows your CNS to run a quasi-classical world-simulation… https://www.youtube.com/watch?v . Or are we to term it a non-physical, not to say a super-physical, law? Wasn’t Darwin supposed to have explained that? Now, design enzymes specific for your needs. No. But until that happens, the field will be hounded by skepticism. An There are hints that cryptochromes in monarch butterflies, which migrate, are sensitive to magnetic effects. Enzymes.Judith Klinman at the University of California, Berkeley, has been studying quantum effects in enzyme catalysis since the late 1980s. The chloroplasts contain structures known as thylakoids that are filled with chlorphyll molecules. His blood letting doctor is also exempt from malpractice. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️🔗 L I N K S 🔗📱Instagram: https://www.instagram.com/patkellyteaches/🐦Twitter: https://twitter.com/PatKellyTeaches💰Patreon: https://www.patreon.com/corporis📽 O T H E R V I D E O S 📽⚰️Medical History playlist: https://www.youtube.com/playlist?list=PL2rpvfNeooNGcIesiheCNuPvuQyRlRavb🔬Anatomy Basics playlist: https://www.youtube.com/playlist?list=PL2rpvfNeooNE5E4jKX9JOrXITW-kIfZCc💪Kinesiology and Biomechanics playlist: https://www.youtube.com/playlist?list=PL2rpvfNeooNGkKlDT2ctqTpPtJgAPOpjx📜 S O U R C E S 📜2005 Schweitzer T rex paper: https://science.sciencemag.org/content/sci/307/5717/1952.full.pdf?casa_token=8FmKWrgSG18AAAAA:nDl_U1f2O-oPEzYcHzsCIhOnYbfl5x9Yt-pNKivaGrq5Wn3xHmwttRmBOCLoU9WT2yqDRoZQ4y39Yiw2007 Schweitzer papershttps://science.sciencemag.org/content/316/5822/277https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1685849/1966 University of Pennsylvania paperhttps://www.cell.com/biophysj/pdf/S0006-3495(66)86698-5.pdf1989 Klinman paperhttps://www.researchgate.net/profile/Christopher_Murray3/publication/224954062_Hydrogen_Tunneling_in_Enzyme_Reactions/links/0fcfd4fb2ca8d12265000000/Hydrogen-Tunneling-in-Enzyme-Reactions.pdfOther Quantum Biology historyhttps://royalsocietypublishing.org/doi/10.1098/rspa.2016.0822#d3e1177Life on the Edge by Johnjoe Mcfadden and Jim Al-Khalili (2014)PHOTOSSchweitzer with T rex by CYNTHIA MATTY-HUBER in Science MagSchweitzer in lab by Evelyn Boswell, MSU News ServiceOther AssetsStopwatch by Kazim Abbas from the Noun Project💊A B O U T 💊Hi, I’m Patrick. These proto-enzymes couple with the environment and so collapse the quantum state of the peptide into a classical state. “If you manage to do the process fast, before the thermal effects take over, that thermal energy becomes irrelevant,” says Schulten. How the oscillatory signal came about became a pressing question in the field. These are the workhorses of the living world, speeding up chemical reactions so that processes that would otherwise take thousands of years happen inside living cells in seconds. “These are the workhorses of the living world, speeding up chemical reactions so that processes that would otherwise take thousands of years happen inside living cells in seconds.”. For that is just what is to be expected from the knowledge we have gained of the structure of living matter. How they achieve this speed-up – often more than a trillion-fold – has long been an enigma. The theoretical modeling by Al-Khalili’s group so far has shown that the amount of hydrogen tunneling occurring in DNA is so rare that it’s insignificant. This means that electrons and protons have a finite probability of being found anywhere within the system based on evolutionary design. –, Bob O'H demonstrates his cluelessness. Found insideThis book presents the hotly debated question of whether quantum mechanics plays a non-trivial role in biology. In a timely way, it sets out a distinct quantum biology agenda. It’s not beyond the bounds of possibility that it can underpin, in a very real and nontrivial way, certain mechanisms and phenomena in biology,” says Al-Khalili. Quantum Biology Jim Al Khalili,a* Samuele Lilliub Prof. Jim-Al-Khalili explains the emerging field of quantum biology and discusses how this new discipline has developed from its inception in the 1920s until fruition in the late 1990s with the discovery of quantum effects in magnetoreception, olfaction, enzyme catalysis, and photosynthesis. If consciousness is a ‘epi-phenomena’ of material reality then consciousness will be found to have no special position within material reality. Quantum biology seeks to explain biological phenomena via quantum mechanisms, such as enzyme reaction rates via tunnelling and photosynthesis energy efficiency via coherent superposition of states. “I never thought it would be called a field,” she says. The collective electronic excitations of interacting chlorophylls were thought to cause the oscillatory signal. Enzyme action. In this review, we summarise the latest progress in quantum biology, including the areas of enzyme-catalysed reactions, photosynthesis, spin-dependent reactions, DNA, fluorescent proteins, and ion channels. “Those are challenging experiments to do,” notes Hore, whose group has being working in the area. Our research pushes at the boundaries of conventional dogmas in the life sciences, and in the application of physics to biosystems, to uncover new insights . Found insideUnderstanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the ... “The biologists looked like they needed some help — they couldn’t understand what a gene was.”. https://youtu.be/almlINDXU5cPart 3 https://youtu.be/NW7VUFgwqg8Paper which caused such a stir (it's behind a pay wall unf. Excerpt: In conclusion, it may very well be said that information is the irreducible kernel from which everything else flows. The explanation will very likely be a big yawn in comparison what happens when these discoveries are scientifically applied to ID theory, which was properly premised to follow this evidence wherever it leads towards explaining how our Creator/creator works. It appears that the most important reaction in the biosphere is exploiting the quantum world to put our food on our table. Antibody interactions that change cytotoxicity. Since we are quantum beings, it means new rules need to be applied to what we believe. The Quantum Biology Lab seeks to understand phonon, exciton, polariton, and plasmon correlations in biomolecular environments that have implications for biological structure and function. It from Bit? Quantum biology is the study of such quantum aspects of living systems. There are more ideas in quantum biology. This is Part 2 of a 3 part mini-series with @Up and Atom about quantum biology. In a new study, researchers showed that quantum light can be used to track enzyme reactions in real time. That was a useful summary to help us stay current in major physics related developments. Edited by two leading experts, and bringing together the foremost practitioners in the field, this up-to . From our own personal conscious experiences we consider it a fact that consciousness exists in aggregates of matter called “living things”. New data suggest motions of the enzyme are critical for the quantum phenomenon to occur. In the late 1960s, American scientists presented evidence of quantum biology at work in enzymes. There is also a hunch that the magnetic navigation of birds also use a quantum effect to measure the direction of Earth’s magnetic field. For that reason, even the most ardent supporters of quantum biology are its biggest skeptics. More than a mere delicacy, the humble lobster could teach us a lot about healthy aging. What if you were told that a single proton or electron can influence the behavior of an entire biological molecule? More uncertain, however, is whether or not these concepts are fundamental to biology and living processes. Gary S. Gaulin, consciousness is not co-terminous with matter. Avian magnetoreception. • Yes, but mostly for "light" particles… • Electrons • Force Fields • Bond-Rearrangement • Electron Transfer • Nuclei • Tunneling - Proton Transfer • Multiple electronic states - Photobiology But then the problem becomes proving that the quantum effects being measured in experimental systems actually happen in the real world. Found insideThis book focuses on some of the most significant advances in enzyme engineering that have been achieved through directed evolution and hybrid approaches. But as more data accumulated, it became obvious the tweak wouldn’t suffice. I.e. Typical experimental conditions in quantum mechanics are near absolute zero, under vacuum and vibrationally isolated — hardly physiological. “The role of the whole protein, through these fluctuating conformations, is to bring things so close that quantum mechanics starts to take over, even at room temperature.”. Tunneling in enzymes. But after years of debate, says Olaya-Castro, a quantum phenomenon was the answer. I long ago (for sake of theory) had to shave all that off. A significant quantum effect in biology involves cellular enzyme reactions where protons use quantum tunneling to move from one molecule to another as the protein shape changes. This book highlighting recent developments in the field is, therefore, a timely addition to the literature and will interest a broad readership in the fields of biochemistry, inorganic chemistry and computational chemistry. In 2010, Scholes’ group demonstrated the phenomenon in aquatic algae, and Engel, now an independent investigator at the University of Chicago, repeated the FMO experiments at higher temperatures. . It’s still fine to search for “information” related clues. To the unprejudiced mind the second principle appears to be much simpler, much more plausible. Found insideFeaturing contributions from renowned authors, including Nobel Laureate Arieh Warshel, this book explores the theories, methodologies and applications in simulations of enzyme reactions. Meet the discipline known as "quantum biology": the idea that the oddities of quantum mechanics play vital roles in the biology of living things. We introduce a quantum model system incorporating qualitative aspects of tunneling in enzyme action and analyze the possibilities of quantum superposition of several conformations of the enzyme-substrate complex. “I didn’t really believe it at first,” says Klinman, recalling her reaction when she first had to consider that quantum mechanical behavior was occurring. The 2000 paper by Schulten’s group pinpointed the spins to cryptochromes, which “gave us all a specific molecule to think about,” says Hore. Quantum Optics Meets Enzyme Biology. Of particular interest to quantum optics is the development of single photon emitters and detectors. “What we need is to develop new kinds of measurements,” says Scholes. . But the experiments, which McFadden’s group is now planning, are difficult to interpret. McFadden uses a traffic jam to explain the quantum phenomenon: “You can go one way or another way to escape the traffic jam. The quantum world exists, whether anything uses it or not, but in nature everything tends to get used. From the time I fell in love with general relativity and gravitation in 1952 until late in my career, I pursued the vision of a world made of fields, one in which the apparent particles are really manifestations of electric and magnetic fields, gravitational fields, and space-time itself. [Image: Simonetta Pieroni] But now the question was how. It’s as simple as that. Let's say giraffes started as elk-type animals, and began eating the lower branches of trees.... –, A major biology organization used the giraffe as proof of evolution by saying longer necked giraffes had greater survival potential.... –, Maybe someone will define creationism correctly. Explores the role of quantum mechanics in biology for advanced undergraduate and graduate students in physics, biology and chemistry. While my profession involved understanding biology and physiology it never entered my mind that quantum physics was involved. “We have to be skeptical,” he says. I focus on a testable model that keeps things as Occam’s Razor simple as possible. In the first period, extending from the beginning of my career until the early 1950?s, I was in the grip of the idea that Everything Is Particles. That new explanation was that a hydrogen, like an electron, was cutting through an energy barrier rather than going over the hump. Al-Khalili and McFadden are studying whether hydrogen tunneling can cause DNA mutations. Our PhD in Quantum Biology gives you the opportunity to undertake an interdisciplinary research programme in a theoretical or experimental area of the discipline. Moreover, the physics of certain enzymes that crawls along DNA and considered as molecular motors or rachets is not well established. All molecules possess thermal energy simply because of their random motions. However, researchers still feel they are not getting a proper look at the mechanism of excitation transport. Quantum effects tend to fade at the level of whole atoms and molecules. Four intersecting lines of experimental evidence from quantum mechanics that shows that consciousness precedes material reality (Wigner’s Quantum Symmetries, Wheeler’s Delayed Choice, Leggett’s Inequalities, Quantum Zeno effect): http://whatislife.stanford.edu.....s-Life.pdf. This emerging and exciting discipline - known as quantum biology - could hold the key to new approaches in solar energy, drugs and diagnostics. Stewart Wills. “Molecular biology was doing very well without quantum mechanics, thank you very much.”. “Quantum mechanics is required to explain so much that underpins physics and chemistry. Read about papers on these and other topics. This volume is the 44th in this classical series. “What came thereafter was that there was this strong sense that quantum mechanics was no longer needed in biology,” says Al-Khalili. Lindau Nobel Laureate Meetings. Measuring quantum phenomena in molecular biology can be an artful arrangement of experimental compromises. We must therefore not be discouraged by the difficulty of interpreting life by the ordinary laws of physics. John Wheeler (1911–2008) summarizes his life in physics – February 2014 What makes quantum biology of today different from the science of yesteryear is that researchers are designing experiments and developing theoretical models based on experimental data. “If you delve into chemistry deep enough, you inevitably come across quantum mechanics, in the sense that the orbital structure of atoms is based on quantum mechanics,” says Johnjoe McFadden at the University of Surrey in the U.K. Quantum biology seeks to explain biological phenomena via quantum mechanisms, such as enzyme reaction rates via tunnelling and photosynthesis energy efficiency via coherent superposition of states. It had always seemed irrelevant for day to day life. The book features interviews with preeminent computational chemists, underscoring the role of collaboration in developing new science. Three of these interviews are new to this edition. http://www.metanexus.net/archi.....linger.pdf, “The thesis of my book ‘Being as Communion’ is that the fundamental stuff of the world is information. The experiments involved replacing hydrogen with its heavier isotopic counterpart deuterium and measuring how the catalytic pace of the enzyme changed. of heat and catalyst o f many biological reactions r elies on q uantum. Quantum biology seeks to achieve a better understanding of quantum mechanics in biological processes. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research ... Karen Bornfeldt, an associate editor for the Journal of Lipid Research, investigates how diabetes increases cardiovascular disease risk. Found insideI am very happy to accept the translators' invitation to write a few lines of introduction to this book. That paper, “On the nature of gene mutation and gene structure,” inspired Schrödinger’s book “What is Life?” The book devoted much attention to quantum effects in biology, with Schrödinger postulating how order at the level of the hereditary material could lead to order on the organismal level. For light atoms, such as hydrogen, this probability area can extend through activation barriers. Would we expect biology (chemistry really) to be be exempt from the world of QM? “Right now, biologists don’t care” about quantum mechanics, says Scholes. Microtubules . In 2009, the group of Ian Mercer at University College Dublin reported similar observations at ambient temperatures with the light-harvesting complex II of a photosynthetic bacterium. An atlas for macrophage activation. https://www.youtube.com/watch?v=cYAsaU9IvnI Click the link below to see the rest of the videos on her channel: https://w. Keywords: autism; consciousness; DNA Quantum mechanics also is thought to be most noticeable at temperatures close to absolute zero. Also, experience tells us that they are rather difficult to create. Anton Zeilinger – a leading expert in quantum teleportation: The motions of the enzyme bring two sites, the acceptor and donor that are needed for the reaction to take place, very close together — so close that the hydrogen can move like a wave to get from one site to another. Enzymes made every single biomolecule in every cell of every living creature on the planet. If one believes there is a creator of the universe then that person is... –, @querius The logic of subjectivity, and objectivity, are just totally different. – J. Found insideThis book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Here is the video I was referring to. The text is highly recommended for undergraduate students in biochemistry who wish to study about enzymes or focus completely on enzymology, as most of the mathematics used in this book, which have been explained in detail to remove most ... Depending on the availability of studentships, you could explore a topic such as photosynthesis, molecular mechanisms of mutation, enzymes, olfaction, nanobiotechnology or synthetic . So everyone was right, and can stop arguing about that now. Quantum biology asks a very simple question: Does quantum mechanics — that weird and wonderful and powerful theory of the subatomic world of atoms and molecules that underpins so much of modern physics and chemistry — also play a role inside the living cell? Just on the molecular-biology front, “we have no idea about what the environment of these proteins might be inside the cell,” says Hore. Quantum biology is the study of such quantum aspects of living systems. either you have it or not have it, there is no ‘I got a little, so let’s optimize to make it more!’. Hydrogen is 2,000 times heavier than an electron. But how accurate is that “1000 years”? Quantum mechanics is essential in explaining the many important processes in life. Therefore, consciousness is found to precede material reality. An example of what does help to develop science changing theory is this I wrote for a forum Keiths knows too for demolishing ID. Quantum biology explains that some of these strange quantum effects can and do occur in biological systems. In 2000, Klaus Schulten’s group at the University of Illinois Urbana–Champaign proposed that magnetoreception relied on cryptochromes, a class of molecules ubiquitous in many species, as the internal compass in birds. Sign up to get updates on articles, interviews and events. A pressing problem with the field of quantum biology is the inability to test and prove unequivocally many of the ideas within its purview. It’s almost certain the proteins will have to be immobilized to stop them rotating inside the cell, because if they do rotate then they won’t be able to sense the rotation of the magnetic field, merely its presence. Found insideCreating a Physical Biology makes the Three Man Paper available in English for the first time. Enzymes use quantum tunnelling? https://www.youtube.com/watch?v=y0beERVJxgs, Marina And The Diamonds – “I Am Not A Robot” Researchers working in this niche are asking if some critical biochemical reactions rely on the split personality of energy as waves and particles. This practical reference explores computer modeling of enzyme reations--techniques that help chemists, biochemists and pharmaceutical researchers understand drug and enzyme action. After all, certain areas of physics and chemistry, such as condensed-matter physics and computational chemistry, make sense only in view of quantum mechanics. and relatively simple as the Sun can use quantum forces, surely the incredibly complex and high number of processes that occur in biological systems, have undiscovered quantum connections. A Short History Of Quantum Mechanics and Consciousness Both areas are most advanced in their experimental data and theoretical underpinnings. Recent research suggests that quantum mechanics appears to play an important role in many biological processes, such as photosynthesis, enzyme action and mutation. Quantum-Chemical Descriptors of Hydroxychloroquine and Remdesivir. They are, more than any other component (even DNA, given that some cells get by without it) the essential ingredient of life. Excerpt: “I think of my lifetime in physics as divided into three periods. The kind of new measurements he’s thinking of will allow researchers actually to see the energy moving through the chlorophyll molecules to the reaction centers. These areas are reviewed by an international team of experts in theoretical, computational chemistry, and biophysics. This book has three sections that group together different aspects of multi-scale quantum simulations. All else that is not needed (to explain how the model works) unnecessarily complicates things in regards to developing scientifically noncontroversial Theory of Intelligent Design. Enzymes, those workhorses of life, the catalysts of chemical reactions . It was natural for scientists to wonder if the underpinning of genetics at the atomic level could be explained by quantum phenomena. New York Times bestseller • Life on the Edge alters our understanding of our world's fundamental dynamics through the use of quantum mechanics.Life is the most extraordinary phenomenon in the known universe; but how did it come to be? That’s where we are at the moment.”, The one thing experts unanimously say is that they need new technologies and methods to delve deeply into the questions being asked about quantum effects in biology. Quantum Light Improves Sensitivity of Biological Measurements. Quantum biology explains that some of these strange quantum effects can and do occur in biological systems. Only to those with very limited minds. It means we haven’t proven biological relevance.”. Rich in its breath and depth, this introduction to modern theories and methods of study is suitable for experienced researchers those new to the subject. Since then, there are some hints that cryptochromes in fruit flies and monarch butterflies (like European robins, monarch butterflies also migrate) are sensitive to a magnetic field. It’s clearly in vogue at the moment,” says Peter Hore at the University of Oxford in the U.K., who is interested in understanding the molecular mechanism by which migratory birds sense Earth’s magnetic field. Blog. Quantum Biology manages organic cycles that are quantum mechanical in nature. I’ve only skimmed the article, but I don’t see the significance of the discovery. Quantum mechanics might even underpin the very existence of life itself. It's not a huge field so you may have to look outside of France. Enzymes.Judith Klinman at the University of California, Berkeley, has been studying quantum effects in enzyme catalysis since the late 1980s. Quantum Tunneling - Enzymes - The Miracle of Metamorphosis - EARTH . Marta Mellini, Ilaria Gianani, Giordano Rampioni and Marco Sbroscia were among the members of a team at the Università degli Studi Roma Tre, Rome, that explored the use of quantum light to enable real-time, accurate measurement of enzyme activity. Quantum mechanics might even underpin the very existence of life itself. That’s the essential point for every human on earth to... –, A new paper is out at Phys.Org Where "Phys.org" is actually Nature Communications. Quantum coherent transport in photosynthesis [31-35], magnetoreception in birds [36-38], quantum olfaction [39-42], single photon detection in vision [43,44], enzyme catalysis [45], motor protein function [46], and even quantum processing with nuclear spins in the brain [47-50] are just a few examples of how nontrivial quantum effects . Al-Khalili also referenced what is to be most noticeable at temperatures close to absolute zero, under vacuum and isolated. 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